If an ink cartridge runs out in the middle of a print, can I replace it and continue?

Yes. There are reports of perfect prints when doing this. However, it is important to note that time is of the essence when ink runs out during printing. If the cartridge is not replaced fast enough the printer will cancel the print and eject the unfinished print. You may want to be around the printer when printing and ink levels are low so you can swap out carts if one runs out without losing the print.